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H2 Chemistry Notes
H2 Chemistry 11 - Organic Chemistry: Nucleophilic Substitution of Halogenoalkanes
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What you will learn
Compares tertiary 2-bromo-2-methylpropane (SN1) with primary 1-bromobutane (SN2) reacting with aqueous NaOH.
SN1: slow heterolytic C-Br fission gives a tertiary carbocation stabilised by three alkyl groups, then fast attack by OH-.
SN2: a single concerted step with hydroxide attacking from the back side while bromide leaves, causing inversion of configuration.
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